Table 4.
PI-88 (mg/day) |
Docetaxel (mg/m2) |
No. patients (No. of courses) |
Bruising at injection site incidence |
Thrombocytopenia incidence |
Anemia incidence |
||||
---|---|---|---|---|---|---|---|---|---|
G1 | G2 | G1 | G2 | G3 | G1 | G2 | |||
106 | 30 | 3 (6) | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
140 | 30 | 3 (5) | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
190 | 30 | 3 (8) | 3 | 0 | 4 | 0 | 0 | 0 | 2 |
250 | 30 | 7 (23) | 1 | 0 | 0 | 0 | 1 | 0 | 2 |
Total | 16 (42) | 5 (12%) | 5 (12%) | 4 (10%) |
G1–G3 represent National Cancer Institute CTC grades 1–3 (version 2.0). The number of cycles in which each toxicity was observed is indicated in the body of the table