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Mechanical thresholds to von Frey hindpaw testing 7 d after SNI or sham surgery. Surgery was performed at P3, P10, P21, or P33. Only animals operated at P33 and adults displayed the mechanical hypersensitivity characteristic of a neuropathic pain-like response. Data are expressed as mean response threshold ± SEM. *p < 0.05, two-way ANOVA, n = 5 animals at each age.
