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Mechanical sensitivity after SNI in Rag1-null animals relative to wild-type littermate controls. Rag1-null mice develop significantly less mechanical sensitivity in the SNI model over a 3 week time course, compared with wild-type littermate controls. All data are mean ± SEM. All values are expressed as means ± SEM. Data were analyzed using two-way ANOVA (time and genotype) for genotype (F(1,4) = 5.3; p < 0.05; post hoc Student's t test, *p < 0.05, n = 9 animals per group).
