Table 3.

Substrate scope in the continuous flow arylation of aldehydes.^a

Entry	Product	Time (h)	Conv (%)	% ee
1		1 2 3 4 Overallb	99 98 98 98 80d (76)e	83 82 81 79 81 (93)e
2		1 2 3 Overallb	99 99 99 91d	58 56 53 55
3		1 2 3 4 Overallb	99 99 99 99 78d (67)e	72 70 67 65 68 (86)e
4		1 2 3 4 Overallb	>99 >99 >99 >99 93d	81 74 70 69 70
5		1 2 3 Overallb	99c >99c 82c 82d	– – – 66
6		1 2 3 4 Overallb	99 >99 >99 97 83d	57 60 62 67 63

^aReaction conditions as in Table 2. For determination of conversion and ee see Supporting Information File 1.

^bData for the whole flow experiment.

^cDetermined by ¹H NMR.

^dIsolated yield.

^eAfter a single recrystallization.