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. Author manuscript; available in PMC: 2010 Apr 1.
Published in final edited form as: Pac Symp Biocomput. 2010:337–347. doi: 10.1142/9789814295291_0036

Table 2.

Summary of the data sets of amino acid substitutions. The number of sites includes the set of unique positions of amino acid substitutions in a particular set.

Data set Number of substitutions Number of sites Number of proteins Source

Putatively neutral (Neutral) 29,190 28,864 10,416 Swiss-Prot
Disease, inherited (Disease-I) 40,512 33,416 2,605 HGMD, Swiss-Prot
Disease, somatic (Disease-S) 3,761 3,191 2,336 Swiss-Prot, Literature