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. 2010 Feb 1;5(2):e8979. doi: 10.1371/journal.pone.0008979

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Kim et al.

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

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(A) Schematic overview of RNAi screens and integrative analysis to identify essential regulators of β-catenin activity and cancer cell proliferation. (B) Immunoblot analysis of CK1ε levels after RNAi-induced suppression. (C) Effects of CSNK1E suppression with two shRNA sequences (A and B) on proliferation. Graph shows mean ± SD of a representative experiment performed in triplicate.