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. 2010 Feb 1;5(2):e8979. doi: 10.1371/journal.pone.0008979

Figure 4. Small molecule inhibition of CK1ε specifically affects breast cancer cells with β-catenin activity.

Figure 4

(A) IC261 dose response curves of β-catenin active cells (MCF7) and β-catenin inactive cells (MDA-MB-453). (B) PF-670462 dose response curves of β-catenin active cells (MCF7) and β-catenin inactive cells (MDA-MB-453). Graphs show mean ± SD of a representative experiments performed in triplicate.