Antibody titers of anti-Sm-p80 total IgG1 in immunized mice. Control prime boost (Cont PB; pcDNA3-ODN-2137), experimental prime boost (Exp PB: Sm-p80-pcDNA3- rSm-p80-ODN-10104), control protein vaccine, Cont Prot Vacc; ODN-2137), and experimental protein vaccine (Exp Prot Vacc; rSm-p80-ODN-10104). a represents the prime boost experiment, while the protein vaccination experiment is shown in b. The values represent the mean of three replicates ± standard error