Table 1.
Immunization group | Number | Worms burden (mean±SE) | Number of eggs/g liver (mean±SE) | Number of eggs/g intestine (mean±SE) | Number of eggs/g tissue(mean±SE) | Percent reduction in worm burden (p≤0.001) | Percent reduction in egg production (p≤0.001) |
---|---|---|---|---|---|---|---|
Control prime-boost (pcDNA-ODN-2137) | 14 | 21.14±2.04 | 7174.08±1544.82 | 1968.45±391.02 | 4571.26±2602.81 | – | – |
Experimental prime boost (Sm-p80-pcDNA3-rSm-p80-ODN-10104) | 15 | 9.06±0.99 | 1967.05±422.37 | 699.85±165.44 | 1333.45±633.60 | 57.14 | 70.82 |
Control protein vaccine (ODN-2137) | 15 | 26.40±1.45 | 6969.39±1147.60 | 2232.36±440.89 | 4600.87±2368.51 | – | – |
Experimental protein vaccine (rSm-p80-ODN-10104) | 15 | 8.40±1.13 | 873.93±460.04 | 389.16±87.17 | 1131.54±742.38 | 69.69 | 75.40 |