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. Author manuscript; available in PMC: 2011 Jan 1.
Published in final edited form as: Cell Mol Neurobiol. 2009 Jul 7;30(1):23. doi: 10.1007/s10571-009-9427-x

Figure 6. Effects of icv leptin administration on food intake in db333/db333, db/db and WT mice.

Figure 6

Injection of leptin (icv 4 µg/µL) caused a significant reduction in food intake in WT mice (P=0.0038) while no significant appetite suppression was observed in db333/db333 or db/db mice. Data are plotted as mean ± SE for n = 4 animals of each genotype. Significant differences between group means are denoted by asterics and were determined by one way ANOVA and post hoc Tukey test.