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Nebivolol reduced renal NADPH oxidase in Ren2 rats. a Total NADPH oxidase activity. b Representative images of semiquantitative immunohistochemistry analysis for NADPH oxidase subunit Rac1. Scale bars = 50 μm. c Corresponding measures of intensity for Rac1, p47phox, and p67phox. ∗ p < 0.05 vs. SD-C (n = 6); ∗∗ p < 0.05, Ren2-N (n = 8) vs. Ren2-C (n = 6).
