Figure 3.

Characterization in a DNA-templated format of array positives resulting from exposure to 500 µM Na₂PdCl₄ at 37 °C for 1 h, or at 25 °C for 20 min. Putative reactions were screened by PAGE and MALDI–TOF mass spectrometric analysis (Supplementary Information). Template architectures and reaction conditions were chosen to match those used in the selection rather than to maximize product yields. Product structures other than those proposed are possible. The green/red fluorescence ratio for the internal standard at 37 °C and 25 °C is 2.9 and 3.5, respectively. For A8 + B3, reactivity was not sufficient to obtain reliable product mass characterization.