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. Author manuscript; available in PMC: 2010 Mar 1.
Published in final edited form as: Shock. 2009 Mar;31(3):227. doi: 10.1097/SHK.0b013e31818347e7

Fig. 1. Tissue-specific role of estrogen in various organs and immune cells after trauma-hemorrhage.

Fig. 1

Protective effects of estrogen after trauma-hemorrhage are mediated via ER-α in the liver, Kupffer cells, alveolar macrophages, splenic macrophages, and splenic T cells, and via ER-β in the heart and lung. Tissue-specific effect of estrogen is not found in the small intestine.