Skip to main content
. Author manuscript; available in PMC: 2010 Dec 1.
Published in final edited form as: Ann Surg. 2009 Dec;250(6):995. doi: 10.1097/SLA.0b013e3181b0ebf8

FIGURE 6.

FIGURE 6

Expression of phosphorylated Akt in Kupffer cells following trauma-hemorrhage or hypoxia. Male C3H/HeN mice were subjected to sham treatment, trauma-hemorrhage or hypoxia as described in Materials and Methods. Each group of animals was given Wortmannin (1 mg/kg body weight, BW), YC-1 (5 mg/kg BW) or vehicle at maximum bleedout time or 30 minutes after induction of hypoxia. Kupffer cell phospho-Akt was determined as described in Materials and Methods. The value of p-Akt was normalized to the protein content. Data are mean ± SE; n= 6 animals/group. *P < 0.05 compared with sham and hypoxia groups; #P < 0.05 compared with all the other groups.