Table 6.

Comparison of hydrophobic interaction due to dimer formation of A and B subunits for Phdpd, Zn-Phdpd, and Zn-Pfprol.

	Phdpd	Zn-Phdpd	Zn-Pfprol	Δ(=Phdpd-Zn-Phdpd)	Δ(=Phdpd-Zn-Pfprol)
ΔASAnp = (monomer* − dimer)	1396	2341	2263	−945	−867
ΔASAp = (monomer* − dimer)	914	1067	1070	−153	−156
Total buried area (Å2)	2310	3408	3333
ΔG HP (kJ/mol)	191	333	320	−142	−129

*Monomer means the summation of ASA of A- and B-subunits.

ASA_np and ASA_p represent accessible surface area of nonpolar (C and S) atoms and polar (N and O) atoms, respectively.

The ASA values were calculated using software [20]. The unit of the ASA value is Ų . ΔG _HP was calculated using (1).