Fig. 3.
Effect of BNZ, KW3902 or both on net proximal reabsorption (GFR-CLi) and fractional proximal reabsorption of lithium (1-FELi). Left panel: Individual experiments. Right panel: Changes from baseline after drug(s) were given. Significant differences are indicated as ∗ p < 0.05 vs. baseline. Bottom panel: Observed changes in proximal reabsorption compared to prediction based on GFR and normal glomerulotubular balance. Symbols below the line of identity connote a primary decrease in proximal reabsorption.