Table 2.
DNA levels following WGA and size fractionation using maternal samples1
| Total DNA | 100–300 bp | 500–700 bp | 1,500–2,000 bp | |
|---|---|---|---|---|
| β-Globin | ||||
| Average of DNA gain | 2,623 ± 1,422 | 1.5 ± 1.1 | 4,867 ± 7,526 | 1,645 ± 2,588 |
| Range of DNA gain | 810–5,158 | 0–3.2 | 1–16,592 | 0–6,634 |
| Positive amplified cases | 7 (100%) | 6 (86%) | 7 (100%) | 5 (71%) |
| Cases with >400-fold amplification | 7 (100%) | 0 (0%) | 4 (57%) | 3 (60%) |
| DYS1 | ||||
| Average of DNA gain | 2,552 ± 3,635 | 1,556 ± 3,009 | 821 ± 2,167 | 4.1 ± 7.5 |
| Range of DNA gain | 1–8,512 | 1–8,229 | 0–5,736 | 0–19 |
| Positive amplified cases | 7 (100%) | 7 (100%) | 4 (57%) | 2 (29%) |
| Cases with >400-fold amplification | 4 (57%) | 3 (43%) | 1 (25%) | 0 (0%) |
1
Total of seven maternal samples (GA = 23.3±10.9) analyzed by WGA following size fractionation. Each case was confirmed to have a male fetus.