Table 1.

Families within the APC superfamily

TC No.	Family name	Family abbreviation	Number of proteins in TCDB	Organismal type
2.A.3.1	amino acid transporter family	AAT	13	B
2.A.3.2	basic amino acid/polyamine antiporter family	APA	6	B
2.A.3.3	cationic amino acid transporter family	CAT	5	E
2.A.3.4	amino acid/choline transporter family	ACT	6	E
2.A.3.5	ethanolamine transporter family	EAT	2	A, B
2.A.3.6	archaeal/bacterial transporter family	ABT	1	A, B
2.A.3.7	glutamate: GABA antiporter family	GGA	1	B
2.A.3.8	L-type amino acid transporter family	LAT	15	B, E
2.A.3.9	spore germination protein family	SGP	3	B
2.A.3.10	yeast amino acid transporter family	YAT	20	E
2.A.3.11	aspartate/glutamate transporter family	AGT	1	A, B
2.A.3.12	polyamine: H+ symporter family	PHS	1	E
2.A.3.13	amino acid efflux family	AAE	1	B
2.A.18	amino acid/auxin permease family	AAAP	26	E
2.A.25	alanine or glycine:cation symporter family	AGCS	3	A, B
2.A.30	cation-chloride cotransporter family	CCC	10	E
2.A.42	hydroxy/aromatic amino acid permease family	HAAAP	6	B

APC = Amino acid/polyamine/organocation.

Family transporter classification (TC) number for the 17 current members of the APC superfamily. In the current study, only the AGCS (TC 2.A.25) family was not included, as it was not known to be a member of the APC superfamily when these studies were initiated. The last four entries are established TC families that were later shown to be members of the APC superfamily.

Their superfamily status is indicated in TCDB by a hyperlink. The original family TC numbers were retained because of the stipulation by the International Union of Biochemistry and Molecular Biology (IUBMB) that the TC system must be a static system of classification.

Organismal type from which the proteins derive: B = bacteria; A = archaea; E = eukaryotes.