Table 2. Contributions of individual mutations to red-shifting in dNeptune.
Reversion from Neptune | Excitation peaka | Emission peaka | εb | φc |
---|---|---|---|---|
none (Neptune) | 600 | 650 | 72000 | 0.18 |
C61S | 597 | 649 | 80000 | 0.18 |
F197Y | 596 | 649 | 56000 | 0.16 |
G41M | 595 | 637 | 60000 | 0.21 |
C158A | 593 | 644 | 97000 | 0.19 |
C61S F197Y G41M C158A (mKate S158A) | 585 | 630 | 75000 | 0.30 |
C61S F197Y G41M (mKate S158C) | 586 | 630 | 63000 | 0.33 |
Excitation and emission maxima in nm.
Maximum extinction coefficient in M-1cm-1 measured by the alkali denaturation method (Chalfie and Kain, 2005; Gross et al., 2000).
Quantum yield of fluorescence.