Table 2.

Comparison of colocalization analysis methods for simulated images with low SNR in Fig. 1, J and K

	PPI J to K	PPI K to J	Correlation
Real value	0.20	0.71	0.38
Pearson's coefficient	N/A	N/A	0.54
Overlap coefficient	0.12	3.33	0.64
Manders' coefficient	0.83	0.84	N/A
Costes' approach	0.72	0.68	N/A
ICCS (image scrambled)	0.51	0.57	N/A
This article	0.31	0.49	0.41