Table 2.

Net cost (£) per life year gained with the introduction of universal, voluntary antenatal screening for different prevalences of women who are unaware that they are HIV positive per 10 000 pregnancies

	Model
Prevalence	1/10 000	1/10 000	15/10 000	15/10 000
Screening costs	£40	£4	£40	£4
Scenario
Reference case*	114 400	7 300	3 300	Cost saving
Discount rate 3%†	76 600	4 400	1 800	Cost saving
Discount rate 7%†	151 600	10 400	5 200	Cost saving
Life years gained, not discounted	30 900	2 000	900	Cost saving
No life years gained for the mother‡	157 700	5 200	Cost saving	Cost saving
Two life years gained for the mother‡	90 800	8 300	5 200	Cost saving
Low uptake of interventions§	138 100	10 800	6 100	Cost saving
High uptake of interventions¶	103 800	5 700	2 100	Cost saving
Low lifetime cost of caring for child infected with HIV††	116 600	9 400	5 500	Cost saving
High lifetime cost of caring for child infected with HIV‡‡	112 200	5 100	1 100	Cost saving

^*Discounted at 5%. Uptake of interventions in the reference case is 75% for treatment with zidovudine, 40% for elective caesarean section, and 95% for formula feeding. Lifetime cost of care for child infected with HIV in the reference case is £178 300. ^†Compared with 5% in the reference case. ^‡Compared with one year in the reference case. ^§Low uptake scenario corresponds to 60% for treatment with zidovudine, 20% for elective caesarean section, and 80% for formula feeding. ^¶High uptake scenario corresponds to 90% for treatment with zidovudine, 60% for elective caesarean section, and 100% for formula feeding. ^††75% of costs of reference case. ^‡‡125% of costs of reference case.