Skip to main content
. Author manuscript; available in PMC: 2010 Jul 1.
Published in final edited form as: Biol Blood Marrow Transplant. 2009 May 13;15(7):777. doi: 10.1016/j.bbmt.2009.03.012

Table 1.

Historical end points in treatment trials for acute GVHD

Study Agents Tested Primary End Point Timing of
Assessment
Levine 2008 [9] Etanercept in combination
with steroids		 Complete response Day 28
Alousi 2008 [47] Etanercept, mycophenolate
mofetil, denileukin diftitox,
or pentostatin in combination
with steroids		 Complete response Day 28
Hockenbery 2007 [38] Oral beclomethasone in
combination with steroids		 Time to treatment failure Day 50
Lee 2004 [46] Daclizumab in combination
with steroids		 Decrease by 1 grade Day 42
Cragg 2000 [39] Antithymocyte globulin in
combination with steroids		 Complete or partial
response		 Day 42
Martin 1996 [36] CD5-specific immunotoxin
in combination with steroids		 Complete response Day 42