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. Author manuscript; available in PMC: 2010 Feb 1.
Published in final edited form as: Nat Rev Immunol. 2008 Dec;8(12):923. doi: 10.1038/nri2449

Figure 1. molecular characteristics shared between adipocytes and macrophages in physiological conditions and metabolic disease states.

Figure 1

An extensive transcriptional signature is common to adipocytes and macrophages. The Venn diagram shows the number of genes that are expressed preferentially or approximately equally by pre-adipocytes, adipocytes and macrophages. Inflammatory genes that are expressed by both macrophages and adipocytes are also listed, as are adipocyte-specific metabolic and other genes that are upregulated during the transformation of macrophages into foam cells14–16,114,115.