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. Author manuscript; available in PMC: 2011 Jan 1.
Published in final edited form as: Dermatol Clin. 2010 Jan;28(1):79. doi: 10.1016/j.det.2009.10.009

Figure 1.

Figure 1

A) Genomic organization of LAMA3 gene, vertical bars represent exons, horizontal line introns. B) LAMA3A and LAMA3B transcript organization; blue exons – common to both transcripts, orange -specific to LAMA3A, grey – specific to LAMA3B, pink – specific to LAMA3B2, Below each transcript is a diagrammatic representation of the domain architecture; LN – laminin N terminal domain, LE – laminin-type epidermal growth factor-like repeats, L4 – globular domain, LCC – laminin coiled coil domain, LG laminin globular domains. C) Laminin α3 containing heterotrimer structure. Color scheme of conserved domains as in B, with purple - Lβ-laminin β chain globular domain. Arrows in LM332 and LM3B32 indicate processing points discussed in the text.