Table 2.

Formation of stable adducts in DNA after incubation with quinones or enzyme-activated catechols

Reactant	Stable adducts, μmol/mol DNA-P
Quinones
Z,Z-DIES-3′,4′-Q	1.10
E,E-DIES-3′,4′-Q	0.89
4″-OCH3-DES-3′,4′-Q	0.59
Catechol/enzymes
3′-OH- DES/Tyr	0.71
3′-OH- DES/LP	1.00
3′-OH- DES/PHS	0.80
3′-OH-Z,Z- DIES/Tyr	0.32
3′-OH-Z,Z-DIES/LP	0.45
3′-OH-Z,Z-DIES/PHS	0.44
3′-OH-E,E- DIES/Tyr	0.35
3′-OH-E,E-DIES/LP	0.47
3′-OH-E,E-DIES/PHS	0.46