Table 14.
Cancer mortality rates in cohorts of children whose mothers underwent diagnostic-x-rays during pregnancya
Number of cancer deaths in exposed and unexposed |
|||||
---|---|---|---|---|---|
Study, Yr Published, Location | Years of Birth | Exposed | Unexposed | Observed - Expected | Var (O-E) |
Diamond EL et al, 1973 Baltimore |
1947–59 | 13/19,889 | 23/35,753 | 0.1 | 8.3 |
Lejeune J et al, 1960 Paris |
1947–52 | 2/491 | 0/468 | 1.0 | 0.5 |
Lewis TLT, 1960 London |
1943–58 | 1/11,443 | 7/33,752 | −1.0 | 1.5 |
Magnin P, 1962 Lyon |
1948–56 | 1/5,353 | 1/5,353 | 0.0 | 0.5 |
Griem ML et al, 1967 Chicago |
1947–49 | 4/982 | 6/1,759 | 0.4 | 2.3 |
Hagstrom RM et al, 1969 Nashville |
1945–49 | 4/634 | 0/655 | 2.0 | 1.0 |
Total | 2.5 | 14.1 |
Source: Doll and Wakeford 1997 [16]