Table 8.
Risk of childhood cancer according to the reason and timing of the prenatal diagnostic x-ray exposure based on medical records: Oxford Survey of Childhood Cancer case-control study
| Reason for X-ray | # Cases X-rayed |
# Controls X-rayed |
Odds Ratios | ||||||
|---|---|---|---|---|---|---|---|---|---|
| Trimester |
Trimester |
||||||||
| 1 | 2 | 3 | All | 1 | 2 | 3 | All | ||
| All Obstetric | 15 | 58 | 1,299 | 1,372 | 7 | 44 | 996 | 1,047 | 1.3 |
| Twins | 3 | 27 | 429 | 459 | 1 | 18 | 316 | 335 | 1.4 |
| Malposition | 0 | 4 | 318 | 322 | 0 | 7 | 271 | 278 | 1.2 |
| Disproportion | 0 | 0 | 133 | 133 | 0 | 0 | 125 | 125 | 1.1 |
| Fetal Abnormality | 0 | 7 | 60 | 67 | 0 | 3 | 34 | 37 | 1.8 |
| Placenta previa | 0 | 0 | 48 | 48 | 0 | 0 | 41 | 41 | 1.2 |
| Pelvimetry | 10 | 14 | 212 | 236 | 5 | 12 | 134 | 151 | 1.6 |
| Prolonged labor | 0 | 0 | 2 | 2 | 0 | 0 | 2 | 2 | 1.0 |
| Fetal maturity | 2 | 6 | 97 | 105 | 1 | 4 | 73 | 78 | 1.4 |
| All Non-Obstetric | 36 | 17 | 18 | 71 | 9 | 14 | 18 | 41 | 1.7 |
| Pyelogram | 7 | 8 | 1 | 16 | 4 | 4 | 3 | 11 | 1.4 |
| Other contrast | 15 | 3 | 1 | 19 | 4 | 4 | 1 | 9 | 2.1 |
| X-ray, no contrast | 14 | 6 | 16 | 36 | 1 | 6 | 14 | 21 | 1.7 |
| All Reasons | 51 | 75 | 1,317 | 1,443 | 16 | 58 | 1,014 | 1,088 | 1.3 |
Source: Gilman et al. 1988 [128]