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. 2010 Feb 2;5(2):e9022. doi: 10.1371/journal.pone.0009022

Figure 2. Specific miRNAs expression regulation during adipogenesis.

Figure 2

Expressions of miRNAs significantly deregulated during differentiation. MiRNAs expression levels are normalized to an internal control and plotted as fold changes in Log2-ratio scale for day 7 vs. day 0 (grey bars) and day 14 vs. day 0 (black bars). Log2-ratios of 2-class comparisons are symmetric around 0 (while a Log2-ratio of 1 means 2-fold up-regulation, a Log2-ratio of −1 means 2-fold down-regulation as compared to day 0 miRNAs levels). Data are expressed as mean ± SEM (n = 6). All the represented miRNAs (70 of the 799 analyzed miRNAs) showed ANOVA P-values <0.0001 for comparisons between groups and fold-changes over 1.2-fold or under −1.2-fold day 0 miRNA expression levels.