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. Author manuscript; available in PMC: 2011 Feb 1.
Published in final edited form as: Mol Pharm. 2010 Feb 1;7(1):138. doi: 10.1021/mp900177r

Table 2.

Directional Permeability of [3H]-agmatine in MDCKII Cell Monolayers

Papp (10 -6 cm/s) A-to-B B-to-A Influx Ratio
(A-to-B/B-to A)
WT-MDCKII 24.4 ± 1.5** 3.29 ± 0.02 7.41
bcrp1-MDCKII 18.6 ± 0.6**!! 3.35 ± 0.01 5.54##
**

p < 0.01 compared with respective B-to-A permeability

!!

p < 0.01 compared with WT A-to-B permeability

##

p < 0.01 compared with WT influx ratio

Results are expressed as mean ± S.D. (n = 3)