Table 2.
Multivariate Relationships between Pediatric Quality of Life Inventory outcomes and cohort characteristics.
| Trouble Sleeping | Low Energy | |||
|---|---|---|---|---|
| Child Report %; OR (95% CI) |
Parent Report %; OR (95% CI) |
Child Report %; OR (95% CI) |
Parent Report %; OR (95% CI) |
|
| No. | No.=237 | No.=214 | No.=234 | No.=222 |
| Measured GFRa | ||||
| ≥50 | 33%; 1 (ref) | 29%; 1 (ref) | 33%; 1 (ref) | 31%; 1 (ref) |
| 40-<50 | 23%; 1.49 (0.78, 2.83) | 23%; 0.88 (0.44, 1.77) | 22%; 1.38 (0.72, 2.65) | 24%; 2.07 (1.05, 4.09)* |
| 30-<40 | 26%; 0.92 (0.49, 1.73) | 28%; 0.75 (0.37, 1.51) | 26%; 1.12 (0.58, 2.17) | 27%; 2.35 (1.17, 4.72)* |
| <30 | 19%; 0.93 (0.46, 1.90) | 20%; 0.77 (0.34, 1.75) | 19%; 1.49 (0.70, 3.17) | 18%; 2.59 (1.15, 5.85)* |
| Family Income | ||||
| ≤ $36,000 | NA | 37%; 1 (ref) | NA | 37%; 1 (ref) |
| $36,000–≤$75,000 | NA | 30%; 0.82 (0.44, 1.52) | NA | 31%; 0.82 (0.44, 1.50) |
| >$75,000 | NA | 33%; 0.54 (0.30, 0.99) * | NA | 32%; 0.32 (0.16, 0.67)* |
| % of life with CKD | ||||
| <25% | NA | NA | 17%; 1 (ref) | 16%; 1 (ref) |
| 25% to <75% | NA | NA | 30%; 0.35 (0.17, 0.71)* | 29%; 0.47 (0.22, 1.02) |
| 75% to 100% | NA | NA | 53%; 0.34 (0.17, 0.65)* | 55%; 0.32 (0.16, 0.67)* |
| Growth Markers | ||||
| Birth Weight <2500g** | NA | 18%; 1.55 (0.81, 2.95) | NA | NA |
| BMI percentileb | ||||
| <35 | 26%; 1 (ref) | NA | NA | NA |
| 35 to <60 | 23%; 1.16 (0.59, 2.30) | NA | NA | NA |
| 60 to <85 | 24%; 0.90 (0.45, 1.79) | NA | NA | NA |
| ≥85 | 27%; 1.96 (1.01, 3.83)* | NA | NA | NA |
| Co-morbidities | ||||
| Hypertensiveb | 48%; 0.59 (0.36, 0.97)* | NA | NA | NA |
| Anemia | NA | 45%; 1.03 (0.58, 1.81) | 41%; 1.66 (0.96, 2.85) | 44%; 1.75 (0.99,3.09) |
| Global P-value for model significance |
P=0.07 | P=0.4 | P=0.005 | P<0.001 |
*
indicates significance at the 0.05 level; OR, odds ratio; CI, confidence interval; CKD, chronic kidney disease; NA, not applicable; ref, reference.
**
reference value is ≥2500 g[ND3]
a
Glomerular filtration Rate measured in ml/min/1.73m2.
b
Age and sex specific percentiles using standard growth charts for United States children.
b
Systolic or Diastolic Blood Pressure >95th percentile for age, sex, height or self-report of hypertension with concurrent report of anti-hypertensive medication.