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. Author manuscript; available in PMC: 2011 Feb 17.
Published in final edited form as: Neuroscience. 2009 Nov 24;165(4):1013. doi: 10.1016/j.neuroscience.2009.11.031

Figure 1.

Figure 1

Field potential measurement of evoked monosynaptic strength. (A) Electrical stimulation was applied in orofacial motor cortex, and evoked potentials were recorded from multiple electrodes in the contralateral striatum. (B) Illustration of stimulation protocol. (C) Monosynaptic strength was estimated as the voltage difference between the first negative (N1) and positive (P1) peaks. Trace is an average from 10 consecutive stimulation events. Stimulation artifact is at 0 ms. (D, E) Sample measurements of series averaged evoked field potentials from a single electrode recorded under both the awake state (D) and the barbiturate anesthetized state (E). Dashed lines indicate epochs used to calculate synaptic strength at baseline and following conditioning.