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. Author manuscript; available in PMC: 2011 Feb 17.
Published in final edited form as: Neuroscience. 2009 Nov 24;165(4):1013. doi: 10.1016/j.neuroscience.2009.11.031

Figure 2.

Figure 2

Direction of plasticity is dependent upon brain state. Eleven animals received 5 Hz stimulation under two brain states, awake/unrestrained and barbiturate anesthesia. Closed markers indicate significant changes in each state, and horizontal lines indicate state means. A two tailed paired samples t-test reveals a significant effect of brain state on plasticity outcome (p=0.002). Seven animals were tested in the awake state first (circles) followed by barbiturate anesthesia. In 3 animals the order of testing was reversed (triangles).