Table 4.
CD4+ | CD8+ | |||||
---|---|---|---|---|---|---|
Group | Day | Na | Meanb (%) | Responders n (%)c | Meanb (%) | Responders n (%)c |
Group 1 | 0 | 54 | 0.0543 | 4 (7.4%) | 0.0540 | 2 (3.7%) |
28 | 54 | 0.0744 | 5 (9.3%) | 0.1828 | 10 (18.5%) | |
42 | 54 | 0.0805 | 10 (18.5%) | 0.5108 | 25 (46.3%) | |
84 | 54 | 0.0538 | 5 (9.3%) | 0.2692 | 16 (29.6%) | |
Group 2 | 0 | 49 | 0.0506 | 4 (8.2%) | 0.0963 | 5 (10.2%) |
28 | 49 | 0.0891 | 8 (16.3%) | 0.2355 | 19 (38.8%) | |
42 | 49 | 0.0672 | 8 (16.3%) | 0.4095 | 25 (51.0%) | |
84 | 49 | 0.0697 | 8 (16.3%) | 0.3693 | 22 (44.9%) | |
Group 3 | 0 | 52 | 0.0263 | 1 (1.9%) | 0.3039 | 3 (5.8%) |
28 | 52 | 0.0512 | 4 (7.7%) | 0.1887 | 14 (26.9%) | |
42 | 52 | 0.0730 | 8 (15.4%) | 0.6525 | 27 (51.9%) | |
84 | 52 | 0.0729 | 5 (9.6%) | 0.3602 | 28 (53.8%) |
N = total number of subjects analysed.
The mean percentage of all CD3+CD69+CD4+ and CD3+CD69+CD8+ responses was determined. In all cases for the calculation of the mean, n = N, except for Group 1/ Day 0 where n = 53.
Number (percentage) of subjects per group showing a positive response. An individual titre above or at the assay cut-off value of 0.14% for CD4+ and 0.25% for CD8+ T cells was counted as positive response.