Table I.
Pre-operative and post-operative data, presented as mean ± standard error
| Weight (kg) | Plasma Cholesterol (mg/dL) | ||||||
|---|---|---|---|---|---|---|---|
| Group | No. | Age (months) | At implant | At removal | Total at implant | Total at removal | HDL at removal |
| Chow, controla | 13 | 8.1 ± 0.5 | 3.8 ± 0.1 | 3.9 ± 0.1 | 34.0 ± 4.4b | 18.2 ± 3.0b | 37.1 ± 3.5 |
| Chow + NAC | 6 | 7.8 ± 0.5 | 4.3 ± 0.2 | 4.4 ± 0.2 | 33.7 ± 5.3c | 33.0 ± 5.1c | 39.3 ± 2.5 |
| Chow + Probucol | 8 | 7.2 ± 0.6 | 4.2 ± 0.1 | 4.3 ± 0.2 | 31.3 ± 4.8d | 25.8 ± 3.6d | 24.2 ± 2.7e |
| High Cholesterola | 13 | 8.4 ± 0.4 | 4.0 ± 0.1 | 3.9 ± 0.1 | 689.4 ± 30 | 1087.7 ± 116.5 | 45.5 ± 2.9 |
| HC + NAC | 7 | 7.5 ± 0.3 | 4.1 ± 0.2 | 3.7 ± 0.1 | 954.2 ± 198.7 | 1118.9 ± 94.2 | 36.8 ± 2.9 |
| HC + Probucol | 8 | 8.2 ± 0.4 | 4.4 ± 0.1 | 4.0 ± 0.1 | 993.1 ± 90.1 | 1257.7 ±131.8 | 23.4 ± 3.2f |
HC = High Cholesterol
a
Data from reference 10
Significant differences (P < .05) are designated as:
b
Between chow control group and all high cholesterol groups
c
Between chow + NAC group and all high cholesterol groups
d
Between chow + probucol group and all high cholesterol groups
e
Between chow control group and chow + probucol group
f
Between high cholesterol and high cholesterol + probucol group