Table II.
Neointima | Graft | ||||
---|---|---|---|---|---|
Group | No. | Total Cellsb | % Macrophagec | Total Cellsb | % Macrophagec |
Chow, control †† | 6 | 163 ± 19 | 0 ± 0.3d | 146 ± 30 | 0 ± 0.2g |
Chow + NAC | 3 | 142 ± 13 | 0 ± 0.0 | 300 ± 50f | 1 ± 0.4h |
Chow + Probucol | 5 | 184 ± 28 | 2 ± 1.1e | 235 ± 42 | 4 ± 2.0i |
High Cholesterol †† | 5 | 195 ± 20 | 26 ± 9.9 | 159 ± 28 | 30 ± 6.0 |
High Cholesterol + NAC | 4 | 130 ±21 | 23 ± 2.9 | 192 ± 16 | 18 ± 2.0j |
High Cholesterol + Probucol | 5 | 133 ± 11 | 16 ± 4.1 | 186 ± 31 | 28 ± 3.6 |
Data from reference 10
Total cell count per 0.0625 mm2
Percent of total number of cells identified as macrophages per 0.0625 mm2
Significant difference between chow control group and all hypercholesterolemic groups (P < .05)
Significant difference between chow + probucol all hypercholesterolemic groups (P < .05)
Significant difference between chow control and chow + NAC group (P < .05)
Significant difference between chow control and all hypercholesterolemic groups (P < .05)
Significant difference between chow + NAC and all hypercholesterolemic groups (P < .05)
Significant difference between chow + probucol and all hypercholesterolemic groups (P < .05)
Difference between high cholesterol and high cholesterol + NAC (P = .06)