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. 1999 Jul 3;319(7201):24–25. doi: 10.1136/bmj.319.7201.24

Table.

Mean glomerular filtration rates (ml/min) in normotensive patients with insulin dependent diabetes at baseline, after 8 years’ follow up, and during pause in treatment in captopril and control groups

Patient No Captopril group
Control group
Baseline 8 Years 8 Years + pause Baseline 8 Years 8 Years + pause
1 100 101 120 141 157* 135*
2 129 125 131 156 131
3 153 131 123
4 96 75 96 39* 47*
5 114 99 122* 87 84
6 112 98 116* 132 106*
7 105 105* 112* 154 68*
8 127 145* 140* 151 143
9 140 127 144 150 161
10 108 70 102* 117 106
11 169 111
12 144 120 121 148 144
13 117 104 118 119
14 110 100 97 108 94*
15 96 108 126 141
16 171 151 166 142 168
17 164 156 161* 145 130
18 128 106 103 146 140
19 104 116 105 122 *
20 130 135 146 117 91*
21 132 122 128 120 112*
22 136 130*
23 120 118
Mean(SD) 126 (24) 114 (23) 126 (21) 129 (18) 119 (32)
*

Patient developed diabetic nephropathy during 8 years of follow up or during treatment pause. 

Difference from baseline significant at P=0.03.