Figure 5.
Effects of ovarian hormones and MA on Fos-immunoreactivity (ir) in the Nucleus Accumbens (A) core and (B) shell, the Basolateral (C) and Central (D) Nuclei of the Amgydala. Adult ovariectomized Sprague-Dawley rats were primed with EB 48 h (5µg) and 24 h (10µg) prior to the day of collection. Four hours before the collection animals, animals received an injection of oil vehicle or 500µg P. MA (5mg/kg) was co-administered on each day of the hormonal priming. A two-way ANOVA followed by Bonferroni t-tests indicated a significant effect of MA treatment on Fos-ir compared to saline-controls (*p<0.05), but not of hormones. Data are represented as means ± SEM. (n = 7 to 8 animals in each group).