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. Author manuscript; available in PMC: 2011 Feb 1.
Published in final edited form as: Exp Mol Pathol. 2009 Oct 2;88(1):210. doi: 10.1016/j.yexmp.2009.09.013

Figure 2. Soluble PECAM chimera reduces pannus formation and joint destruction even when given after symptoms.

Figure 2

The histopathology score for mice in each treatment group is shown. The average combined score across all four joints (2 fore and 2 hind) is shown for each mouse as an individual dot. The mean value for each group is shown (bar). A) Mice were treated with mPECAM-Fc or human IgG1 every other day. B) Mice were treated every third day. In both experiments, arthrogen-treated mice (Arth) treated with mPECAM-Fc had a significantly lower mean histopathology score than arthrogen-treated mice treated with control IgG (* t-test, p<0.05).