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. Author manuscript; available in PMC: 2011 Apr 1.
Published in final edited form as: Cell Signal. 2009 Nov 20;22(4):584. doi: 10.1016/j.cellsig.2009.11.010

Table.

Summary of Findings

Ad.β1AR vs Control Ad.AC6 vs Control
Transgene location PM PM, NE, SR, MM, Cytoplasm
Follistatin family proteins Increased 4-fold No change
Phospho-p38 Increased 3-fold No change
Phosphatidylserine
translocation
To external PM,
marked
No change
PKA & EPAC
activity/expression
No change No change
PHLPP2 activity No change Inhibited
Akt activity No change Increased 5-fold
p70S6 kinase phosphorylation Decreased Increased 2-fold
Bcl2 expression No change Increased 2-fold
Apoptosis Increased 2-4 fold No change

PM, plasma membrane; NE, nuclear envelope; SR, sarcoplasmic reticulum; MM, mitochondrial membrane. The findings are summary of data from three or more experimental repeats.