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. Author manuscript; available in PMC: 2011 Jan 15.
Published in final edited form as: J Neurosci Methods. 2009 Oct 20;185(2):264. doi: 10.1016/j.jneumeth.2009.10.008

Figure 1. Cannula and SG-2 MEA for real-time in vivo amperometric measurements of glutamate in NHPs.

Figure 1

A) Guide cannula for access to the NHP putamen, with stainless steel cap; B) SG-2 MEA, inset: side-by-side comparison of SPENCER® Probe Depth Electrode and SG-2 MEA; C) magnification of electrode tip showing four platinum recording sites (15 × 333 µm each). The lower pair was prepared for the measurement of glutamate by application of glutamate oxidase (+GluOX). The upper ‘sentinel’ pair did not have glutamate oxidase (-GluOX). This MEA configuration allowed self-referenced glutamate recordings.