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. Author manuscript; available in PMC: 2011 Feb 12.
Published in final edited form as: J Mol Biol. 2009 Nov 10;396(1):47. doi: 10.1016/j.jmb.2009.11.005

Figure 7.

Figure 7

X-ray structure of Y221G/cefotaxime (2.3 Å). (a) Stereo view of quality of density of cefotaxime in the active site of Y221G. 2Fo-Fc density (blue) is shown at a contour level of 1σ, and Fo-Fc.omit density (green) is shown at a contour level of 3σ. (b) The Y221G/cefotaxime structure (orange) overlaid with the WT/ceftazidime structure (green). (c) The Y221G/cefotaxime structure (orange) overlaid with the WT/loracarbef structure (purple). (d) The Y221G/cefotaxime structure (orange) overlaid with the WT/ceftazidime deacylation transition state analog (gray).