Table A. Baseline characteristics of individuals exposed to patients with active tuberculosis (ATBI).
Skin test reactions were measured in all individuals and responsiveness was assessed based on the diameter (mm) of induration after PPD antigen intradermal administration. Cohort 1 shown in the left was used as exploratory to determine the frequency of negativity of TST in the high-risk group. Cohort 2 shown in the right risk confirmed the high frequency of TST negatives in the high-risk group, compared with the group B of the hospital employees.
Cohort 1 | Cohort 2 | Controls | |||||
---|---|---|---|---|---|---|---|
High Risk | Hospital Employees | High Risk | Hospital Employees | Unknown exposure to ATBI |
|||
Personal Contacts |
Hospital(Nurses) | Hospital employees |
Personal Contacts |
Hospital (Nurses) |
Hospital employees |
||
Group A | Group B | Group A | Group B | ||||
n=29 | n=40 | n=31 | n=12 | n=30 | n=49 | n=49 | |
Age (mean, +/− SD) | 43, +/− 16.4 | 40, +/− 7.9 | 43, +/− 9.9 | 47 +/− 17.6 | 37 +/− 11.8 | 38 +/− 8.1 | 33 +/− 10 |
Gender (n, %) | |||||||
Male | (7) 24 % | (4) 7 % | (14) 45% | (7) 58% | (6) 20% | (16) 33% | (22) 45% |
Female | (22) 76 % | (37) 93% | (17) 55% | (5) 42% | (24) 80% | (33) 67% | (27) 55% |
BCG Vaccine (n, %) | |||||||
Yes | (12) 75% | (34) 95% | (29) 94% | (10) 83% | (29) 97% | (43) 82% | (49) 100% |
No | (4) 25% | (2) 5% | (2) 6% | (2) 17% | (1) 3% | (6) 12% | (0) 0% |
TST (n, %) | |||||||
Positive | (8) 28% | (22) 55% | (18) 58% | (2) 17% | (12) 40% | (31) 51% | N.D. |
5–9 mm | 3 | 3 | 3 | 0 | 3 | 6 | N.D. |
10–14 mm | 4 | 8 | 5 | 0 | 5 | 10 | N.D. |
15 or more mm | 1 | 11 | 10 | 2 | 4 | 14 | N.D. |
Negative | (21) 72% | (18) 45% | (13) 42% | (10) 83% | (18) 60% | (18) 37% | N.D. |