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Cox-2 inhibitors do not significantly influence B cell antibody secretion. Unstimulated splenocytes (C57BL/6) were cultured for 48 hours in the presence of vehicle, SC-58125 (2.5, 5, 10 or 20 µM) or NS-398 (5, 10 or 20 µM). Supernatant levels of total IgM (A) and IgG (B) were determined by ELISA. Data are represented as mean ± SEM, * p <0.05.
