Table 2.
Expression of RGC-32 protein in normal colon, inflamed non neoplastic colon tissue, benign and malignant colon tumors
| Tissue | Staining intensity |
Positive / Total cases | |||
|---|---|---|---|---|---|
| − | + | ++ | +++ | ||
| Normal colonic mucosa | 5 | 10 | 7 | 0 | 17/22 |
| Non cancer cases | 5 | 7 | 3 | 0 | 10/15 |
| Cancer cases | 0 | 3 | 4 | 0 | 7/7 |
| Adenomas | 4 | 8 | 7 | 5 | 20/24 |
| Small | 3 | 6 | 6 | 2 | 14/17 |
| Large | 1 | 2 | 1 | 3 | 6/7 |
| Inflamatory bowel disease - colon mucosa (Ulcerative colitis/ Crohn’s disease) | 1 | 5 | 4 | 3 | 12/13 |
| Colorectal adenocarcinoma | 0 | 10 | 28 | 25 | 63/63 |
| Stage T1/T2 | 0 | 2 | 9 | 3 | 14/14 |
| Stage T3/T4 | 0 | 8 | 19 | 22 | 49/49 |
| Metastatic adenocarcinoma | 0 | 1 | 6 | 7 | 14/14 |
| Local lymph nodes | 0 | 1 | 3 | 3 | 7/7 |
| Distant sites | 0 | 0 | 3 | 4 | 7/7 |
−, negative; +, slightly positive; ++, positive; +++, highly positive;