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Effect of 1-min tumor sonication by 90-kHz ultrasound on the droplet-to-bubble conversion in tumor tissue. Formation of microbubbles is manifested by increased brightness of the preexisting bright specks visible in panel (A) and formation of new bright specks (compare panels (A) and (B); specks of interest are indicated by arrows). With time, highly localized bright specks disappear leaving behind lines with a slightly increased brightness (C); K – kidney.
