Fig. 5.
Fertility analysis of null and heterozygous animals. Mating cages were monitored for a period of 6 months to ascertain the average number of litters/month (A) and pups/litter (B). Although there were no significant differences between groups when calculated in this manner (p>0.05 by one-way ANOVA), we did notice that 2 out of the 6 129S5-Tcam-/- mating cages showed a delay in full fertility producing 1 or no pups in their first litter (C). Values in the graphs represent the mean of each sample group (n=4, 9, and 6 for each group respectively), and error bars indicate the standard error of the mean.