Table 2.
Odds ratios for risk of aneurysmal subarachnoid hemorrhage according to genotype
| Genotype | Patients* | Controls** | Odds ratio (95% CI) |
|---|---|---|---|
| FV Leiden | n = 207 | n = 763 | |
| GG | 196 (94.7%) | 721 (94.5%) | 1 (reference) |
| GA and AA | 11 (5.3%) | 42 (5.5%) | 0.9 (0.5–1.8) |
| Prothrombin G20210A | n = 207 | n = 763 | |
| GG | 200 (96.6%) | 745 (97.6%) | 1 (reference) |
| GA and AA | 7 (3.4%) | 18 (2.4%) | 1.5 (0.6–3.5) |
| MTHFR C677T | n = 207 | n = 764 | |
| CC and CT | 185 (89.4%) | 695 (91.0%) | 1 (reference) |
| TT | 22 (10.6%) | 69 (9.0%) | 1.2 (0.3–2.0) |
| FXIII A Val34Leu | n = 208 | n = 747 | |
| ValVal | 122 (58.7%) | 419 (56.1%) | 1 (reference) |
| ValLeu and LeuLeu | 86 (41.3%) | 328 (43.9%) | 0.9 (0.7–1.2) |
| FXIII A Tyr204Phe | n = 207 | n = 754 | |
| TyrTyr | 188 (90.8%) | 711 (94.3%) | 1 (reference) |
| TyrPhe and PhePhe | 19 (9.2%) | 43 (5.7%) | 1.7 (0.9–2.9) |
| FXIII A Pro564Leu | n = 194 | n = 751 | |
| ProPro | 114 (58.8%) | 466 (62.0%) | 1 (reference) |
| ProLeu and LeuLeu | 80 (41.2%) | 285 (38.0%) | 1.2 (0.8–1.6) |
| FXIII B His95Arg | n = 196 | n = 730 | |
| HisHis | 151 (77.0%) | 609 (83.4%) | 1 (reference) |
| HisArg and ArgArg | 45 (23.0%) | 121 (16.6%) | 1.5 (1.0–2.2) |
*For the genotype analysis of the patients the percentage of missing genotypes is 2%
**For the genotype analysis of the controls the percentage of missing genotypes is 18%
CI = confidence interval