TABLE 1.
Disease expression upon mycobacterial inoculation
| Group | Gross pathologya | Culture scoreb |
|---|---|---|
| M. bovis (n = 5) | All positive | 27.2 ± 7.3 |
| M. tuberculosis (n = 5) | All negative | 13.9 ± 5.5 |
| M. kansasii (n = 4) | All negative | 0 ± 0 |
Gross lesions were confirmed to be tuberculous upon histologic evaluation and culture of lung tissue as well as lung- and head-associated lymph node tissues.
Cumulative score (mean ± SEM) based on a ranking of the total numbers of CFU per plate of lung tissue and lung-associated lymph node tissue homogenates at the highest dilution. Mycobacteria were not detected in any tissues collected from M. kansasii-inoculated animals. Mean scores reflect the results from each animal within the treatment group, including culture-negative animals. The results differ (P < 0.05) according to mycobacterial treatment: M. bovis-inoculated animals > M. tuberculosis-inoculated animals > M. kansasii-inoculated animals.