TABLE 2.
Kinetics of serum antibody responses to MPB83, ESAT-6, and CFP-10 in cattle during experimental mycobacterial infection detected by VetTB Stat-Pak lateral-flow assay
| Group | No. of animals positive/no. of animals tested at the following wk after inoculation: |
|||||
|---|---|---|---|---|---|---|
| 0 | 3 | 6 | 9 | 12 | 18a | |
| M. bovisb | 0/4 | 4/4 | 4/4 | 3/4 | 3/4 | NAc |
| M. tuberculosis | 0/5 | 5/5 | 4/5 | 2/5 | 0/5 | NA |
| M. kansasii | 0/4 | 0/4 | 0/4 | 2/4 | 1/4 | 4/4 |
a
For the M. kansasii-inoculated cattle, the responses at 18 weeks were 2 weeks after the injection of PPD for the skin test.
b
One of the M. bovis-infected cattle was euthanized at week 6, and therefore, kinetics data were available for only four of the five original study animals.
c
NA, animals in the M. tuberculosis- and M. bovis-inoculated groups were euthanized 16 weeks after inoculation; thus, samples were not available for analysis at that time point.