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Anti-L. infantum IgG1 and IgG2 responses increase with CVL disease progression. L. infantum-specific IgG responses were measured via ELISA using sera from a control (one dog), noninfected (two dogs), infected resistant (four dogs), infected susceptible (two dogs), and clinical (three dogs) animals. Blood samples were collected and centrifuged to clarify serum. Results shown are OD values from the antigen-specific IgG1 (A) and IgG2 (B) ELISAs. Lines indicate mean values for each group.
